The early days of Kittanning were characterized by the emergence of a few businesses. There were three merchants and one lawyer living in Kittanning, and there were four joiners, rough carpenters, and shoemakers. A blacksmith and a tailor were also found, as well as a hatter, tanner, and three single men.
Originally, Kittanning's river crossing facilities were skiffs and flatboats, which were poled and rowed. Eventually, a ferry was built at the mouth of Jacob street. It carried about thirty or forty passengers and three tons of freight.
In 1854, the Kittanning borough subscribed to significant amounts of Allegheny Valley railroad and Kittanning Bridge stock. Throughout the early nineteenth century, this borough grew steadily and prospered. By 1870, Kittanning had more than 2,500 people, largely due to the coal-mining industry.
In 1858, the Associate Presbyterian and Reformed Presbyterian Churches merged and formed the United Presbyterian Church of North America. The First United Presbyterian congregation in Kittanning is currently under the care of the Butler presbytery. Since the resignation of Dr. Dick, the church has been dependent on presbytery supplies. It is expected that another pastor will be called to serve before the fourth of July. The First United Presbyterian Church is located on Jefferson and Jacob streets and sits on Lot 166.
In 1822, a party celebrating the birthday of Washington was held at the house of John Mechling in Kittanning. The gathering lasted about fifteen hours. On June 28, 1828, Gen. Andrew Jackson requested to meet with these friends. He wanted to consult with these men about the American independence celebration.